Pediatric Liver transplant in Gleneagles Global Hospitals
Hyderabad: The Gleneagles Global Hospitals Hyderabad is delighted to share the success story of two pediatric transplants performed in recent weeks. The recipients were not only transplanted for very severe, advanced end-stage liver disease, but also had unique physical attributes which made the whole exercise of transplantation very daunting.
Master Sai Ganesh, 5 years old young boy from Vijayanagaram, reported to the hospital in the month of June 2018, with a severe liver disease. The boy had been taken to other transplant centers in the state and in South India but was not accepted for liver transplantation on account of very poor health status, as well as the presence of situsinversus. This condition is congenital, wherein organs in the human body are in a 'mirror-image' location-- that is organs normally located on the right side of the body are located on the left, and vice versa.
The surgery was an extremely challenging one, but the surgical team comprising of lead surgeons Dr. K Venogopal and Dr. Balbir Singh successfully implanted a part of the liver taken from the child's father into the child, after removing the diseased liver. The anesthetic management of the child was equally challenging, but the experienced transplant anesthesia team comprising of Dr. Ravi Chandra, Dr. Mohan and Dr. Gopi were equal to the task and carried out the surgery and post-operative care of the child remarkably well.
Baby Selam Devi, then 8 years old girl from Khammam, had been suffering from a chronic cholestatic liver disease for many months before she was reported to Gleneagles Global Hospitals. She had been evaluated at other centers in the state, but was not considered for transplantation on account of being 'too sick'. At Gleneagles Global Hospitals the patient was optimized medically, and then listed for transplant. However, the biggest stumbling block came in the form of non-compatibility of blood group between donor (mother, blood group A1) and the recipient (blood group O). Traditionally, patients with blood group O can receive organs only from identical blood group donors. When such incompatible solid organ transplants are performed beyond infancy, the graft loss rates are extremely high, unless the level of immunosuppression (medicines are given to suppress the recipient's immune system, so that it would not turn hostile against the graft) is escalated substantially.
Baby Selam was not an ideal candidate for this approach, as she was too sick and her blood parameters were not suitable for heightened immunosuppression. This challenging situation was admirably managed by the treating team comprising of Dr. Prashanth Bachina from Rainbow Hospitals Hyderabad and Dr. Prashanth Shinde from Gleneagles Global Hospitals, Hyderabad. They used a novel strategy of immunosuppression to thwart graft rejection in the early post-operative period.
The experience of these two pediatric transplants has once again proven that with meticulous planning and excellent team approach, the most challenging clinical scenarios can also be turned to success stories. Gleneagles Global Hospitals Hyderabad has set the benchmark in liver transplantation, not just in our state, but the entire country, for more than a decade and a half. These two children along with their relieved and happy parents are a reason enough for 'Team of Gleneagles Global Hospitals' to continuously keep improving and innovating.